Diversity and Potential of Herb Vegetation in Forest Area With Special Purpose (KHDTK) Kaliurang Yogyakarta as Medicines
Abstract
Information on the diversity of plants, especially herbs and their potential as medicines is not widely known. This study aims to determine the diversity of herbs and their potential as medicines in the research forest area of Mount Merapi, KHDTK Kaliurang, Yogyakarta. The study in three areas found 27 species herbs with Centhoteca lappacea (L) Desv had the highest average Important Value Index (79.26 %) and Fimbristylis dichotoma (L.) Vahl as the lowest (2.66 %). The Diversity Index (H’) of herbs in KHDTK Kaliurang is low (0.58-0.78). Its use and potential as medicines are found in 21 out of 27 herbs species. These herbs have been widely used for traditional medicine in many countries and further research also show the potential of these herbs for various diseases such as treatment of wounds, urinary problem, fever, diarrhea, anti-oxidant, diabetes, and cancer. Results of this study are expected to provide information on the potential of herbs for traditional and modern medicine. Furthermore, information on the diversity of these herbs can also complement the type of plants in the Mount Merapi region and increasing awareness on the importance of supporting efffort to utilize and preserve the herbs of the Merapi Mountain region, especially in the KHDTK Kaliurang.
Keywords: diversity, herb, medicine, conservation, KHDTK Kaliurang
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Abdiyani, S. (2008). Keanekaragaman jenis tumbuhan bawah berkhasiat obat di Dataran Tinggi Dieng. Jurnal Penelitian Hutan dan Konservasi Alam, V(1), 79-92.
Adebayo, A. H., Tan, N. H., Akindahunsi, A. A., Zeng, G. Z., & Zhang, Y. M. (2010). Anticancer and antiradical scavenging activity of Ageratum conyzoides L. (Asteraceae). Pharmacognosy Mag, 6(21), 62-66.
Adjei, S., Amoateng, P., Osei-Safo, D., Sasu, C., N’guessan, B. B., Addo, P., & Asiedu-Gyekye, J. I. (2014). Sub-acute toxicity of a hydro-ethanolic whole plant extract of Synedrella nodiflora (L) Gaertn in rats. International Journal on Green Pharmacy, October-December 2014, 271-275.
Afrianto, W. F., Hikmat, A., & Widyatmoko, D. (2016). Komunitas floristik dan suksesi vegetasi setelah erupsi 2010 di Gunung Merapi Jawa Tengah. Jurnal Biologi Indonesia, 12(2), 265-276.
Ahmad, I. (2015). Aktivitas anti bakteri dari fraksi daun Bandotan (Ageratum conyzoides L.) secara kromatografi lapis tipis bioautografi. J. Trop. Pharm. Chem, 3(1), 29-36.
Ahmad, F. B., & Ismail, G. (2003). Medicinal plants used by Kadazandusun communities around crocker range. ASEAN Review of Biodiversity and Environmental Conservation (ARBEC), January-March 2003, 1-10.
Ali, N. A. A., Julich, W. D. C., & Lindequist, U. (2001). Screening of Yemeni medicinal plants for antibacterial and cytotoxic activities. Journal of Ethnopharmacology, 74, 173-179.
Amoateng, P., Koffuor, G. A., Sarpong, K., & Agyapong, K. O. (2011). Free radical scavenging and anti-lipid peroxidative effects of a hydro-ethanolic extract of the whole plant of Synedrella nodiflora (L.) Gaertn (Asteraceae). Free Radicals and Antioxidants, 1(3), 70-78.
Amoateng, P., Woode, E., & Kombian, S. B. (2012). Anticonvulsant and related neuropharmacological effects of the whole plant extract of Synedrella nodiflora (L.) Gaertn (Asteraceae). J. Pharm Bioallied Sci., 4(2), 140-148.
Amoateng, P., Adjei, S., Osei-safo, D., Ameyaw, E. O., Ahedor, B., N’guessan, B. B., & Nyarko, A. K. (2015). A hydro-ethanolic extract of Synedrella nodiflora (L.) Gaertn ameliorates hyperalgesia and allodynia in vincristine-induced neuropathic pain in rats. Journal of Basic and Clinical Physiology and Pharmacology, 26(4), 383-394.
Anitha, V. T., Antonisamy, J. M., & Jeeva, S. (2012). Anti-bacterial studies on Hemigraphis colorata (Blume H. G. Haliier and Elephantopus scaber L. Asian Pacific Journal of Tropical Medicine, 52-57.
Balekar, N., Nakpheng, T., Katkam, N. G., & Srichana, T. (2012). Wound healing activity of ent-kaura-9 (11), 16-dien-19-oic acid isolated from Wedelia trilobata (L.) leaves. Phytomedicine, 19(13), 1178-1184.
Barua, C., Roy, J. D., Buragohain, B., Barua, A. G., Borah, P., & Lahkar, M. (2009). Anxiolytic effect of hydroethanolic extract of Drymaria cordata L Willd. Indian Journal of Experimental Biology, 47, 969-973.
Bazylko, A., Borzym, J., & Parzonko, A. (2015). Determination of in vitro antioxidant and UV protecting activity of aqueaous and ethanolic extracts from Galinsoga parviflora and Galinsoga quadriradiata herb. Journal of Photochemistry and Photobiology Biology, 148, 189-195.
BBPPBPTH (Pusat Litbang Bioteknologi dan Pemuliaan Tanaman Hutan). (2004). Sekilas tentang hutan penelitian Kaliurang. Yogyakarta: Departemen Kehutanan, Badan Litbang Kehutanan, Pusat Litbang Bioteknologi dan Pemuliaan Tanaman Hutan.
Bhogaonkar, P. Y., Dagawal, M. J., & Ghorpade, D. S. (2011). Pharmacognostic studies and antimicrobial activity of Synedrella nodiflora (L.) Gaertn. Bioscience Discovery, 2(3), 317-321.
Burlakoti, C., & Kunwar, R. M. (2008). Folk herbal medicines of mahakali watershed area, Nepal. Medicinal Plants in Nepal: An Anthology of Contemporary Research, 2008, 187-193.
Calixto, J. B., Santos, A. R. S., Filho, V. C., & Yunes, R. A. (1998). A review of the plants of the genus Phyllanthus: their chemistry, pharmacology, and therapeutic potential. Res Rev, 4, 225-258.
Daisy, P., Jasmine, R., Ignacimuthu, & Murugan, E. (2009). A novel steroid from Elephantopus scaber L. and ethnomedicinal plant with antidiabetic activity. Phytomedicine, 16(2-3), 252-257.
Das, S., Padhy, J. K., & Panda, P. (2017). Bioactive potential of Tridax procumbens L. leaf extract against skin infection causing bacteria. International Journal of Herbal Medicine, 5(3), 127-133.
Debnath, G., Dutta, S., Saha, A. K., & Das, P. (2016). Green synthesis, characterization and antibacterial activity of silver nanoparticles (Agnps) from grass leaf extract Paspalum conjugatum P.J. Berguis. Journal of Mycopathological Research, 54(3), 371-376.
Deepa, M. R., Dharmapal, S., & Udayan, P. S. (2016). Medicinal plants in the selected sacred groves of Kodungallur, Thrissur district, Kerala. Journal of Medicinal Plants Studies, 4(3), 149-155.
Djufri. (2012). Analisis vegetasi pada savana tanpa tegakan akasia (Acacia nilotica) di Taman Nasional Baluran Jawa Timur. Jurnal Biologi Edukasi, 4(2), 104-111.
Duarte, F. S., Duzzioni, M., Mendes, B. G., Pizzolatti, M. G., & Lima, T. C. M. D. (2007). Participation of dihydrostyryl-2-pyrones and styryl-2-pyrones in the central effects of Polygala sabulasa (Polygalaceae), a folk medicine topical anesthetic. Pharmacology, Biochemistry, and Behaviour, 86, 150-161.
Ernawati, Y. (2014). Keanekaragaman tanaman obat pada ketinggian tempat yang berbeda di sekitar jalur selatan pendakian Gunung Lawu Jawa Tengah. Thesis tidak diterbitkan. Universitas Muhammadiyah Surakarta, Surakarta.
Ferheen, S., Aziz-Ur-Rehman, Afza, N., Malik, A., Iqbal, L., Rasool, M. A., Ali, M. I., & Tareen, R. B. (2009). Galinsosides A and B, biactive flavonone glucosides from Galinsoga parviflora. Journal of Enzyme Inhibition and Medicinal Chemistry, 24(5), 1128-1132.
Floyd, M. L., Fleischner, T. L., Hanna, D., & Whitefield, P. (2003). Effects of historic livestock grazing on vegetation at Chaco Culture National Historic Park, New Mexico. Conservation Biology, 17(6), 1703-1711.
Handayani, T. (2012). Petunjuk Praktikum Ekologi Tumbuhan. Yogyakarta: Fakultas MIPA UAD
Handayani, A. (2015). Pemanfaatan tumbuhan berkhasiat obat oleh masyarakat sekitar Cagar Alam Gunung Simpang, Jawa Barat. dalam Setyawan, A. D., Sugiyarto, Pitoyo, A., Hernawan, U. E., Sutomo, Widiastuti, A., Raqib, S. M., Suwandhi, I., Rosleine, D., Syamsudin, T., Iskandar, J., Simbala, H. E. I., Kilowasid, L. M. H. (eds) Seminar Nasional Masyarakat Biodiversitas Indonesia (p.1425-1432). Surakarta: Masyarakat Biodiversitas Indonesia, Program Biosains Program Pasca Sarjana Universitas Sebelas Maret Surakarta, Jurusan Biologi MIPA Universitas Sebelas Maret Surakarta.
Hariyadi, B., & Tictin, T. (2012). Uras: Medicinal and ritual plants of Serampas, Jambi Indonesia. Ethnobotany Research & Applicants, 10, 133-149.
Hazalin, N. A. M. N., Ramasamy, K., Lim, S. M., Wahab, I. A., Cole, A. L. J, & Majeed, A. B. A. (2009). Cytotoxic and antibacterial activities of endophytic fungi isolated from plants at the National Park, Pahang, Malaysia. BMC Complementary and Alternative Medicine, 9, 46.
Heredia-Diaz, Y., Garcia-Diaz, J., Lopez-Gonzalez, T., Chil-Nunez, I., Arias-Ramos, D., Escalona-Arranz, J. C., Gonzalez-Fernandez, R., Costa-Acosta, J., Suarez-Cruz, D., Sanchez-Torres, M., & Martinez-Figueredo, Y. (2018). An ethnobotanical survey of medicinal plants used by inhabitants of Holguin, Eastern Region, Cuba. Bol Latinoam Caribe Plant Med Aromat, 17(2), 160-196.
Hilwan, I., & Masyrafina, I. (2015). Keanekaragaman jenis tumbuhan bawah di Gunung Papandayan Bagian Timur, Garut, Jawa Barat. Jurnal Silvikultur Tropika, 6(2), 119-125.
Hutasuhut, M. A. (2018). Keanekaragaman tumbuhan herba di Cagar Alam Sibolangit. Klorofil, 1(2), 69-77.
Hynniewta, S. R., & Kumar, Y. (2008). Herbal remedies among the Khasi traditional healers and village folks in Meghalaya. Indian Journal of Traditional Knowledge, 7(4), 581-586.
Isa, M. (2014). Identifikasi kandungan senyawa kimia pada Wedelia biflora dan uji bioaktivitasnya sebagai antiplasmodium berghei. Jurnal Medika Veterinaria, 8(1), 51-55.
Iswandono, E., Zuhud, E. A. M., Hikmat, A., & Kosmaryandi, N. (2015). Pengetahuan etnobotani Suku Manggarai dan implikasinya terhadap pemanfaatan tumbuhan hutan di Pegunungan Ruteng. Jurnal Ilmu Pertanian Indonesia (JIPI), 20(3), 171-181.
Jansen, I., Wuisan, J., & Awaloei, H. (2015). Uji efek antipiretik meniran (Phyllantus niruri L.) pada tikus wistar (Rattus norvegicus) jantan yang dinduksi vaksin DPT-HB. Jurnal e-Biomedik (eBm), 3(1), 470-474.
Jumiarni, W. O, & Komalasari, O. (2017). Eksplorasi jenis dan pemanfaatan tumbuhan obat pada masyarakat suku Muna di permukiman kota Wuna. Trad. Med. J., 22(1), 45-56.
Kabeer, F. A., Sreedevi, G. B., Nair, M. S., Rajalekshmi, D. S.,
Gopalakrishnan, L. P., Kunjuraman, S., & Prathapan, R. (2013). Antineoplastic effects of deoxyelephantopin, a sesquiterpene lactone from Elephantopus scaber, on lung adenocarsinoma (A549) cells. Journal of Integrative Medicine, 11(4), 269-277.
Kagyung, R., Gajurel, P. R., Rethy, P., & Singh, B. (2010). Ethnomedical plants used for gastro-intestinal diseases by Adi tribes of Dehang-Debang biosphere reserve in Arunachal Pradesh. Indian Journal of Traditional Knowledge, 9(3), 496-501.
Kahono, J. Y. (2010). Pengaruh ekstrak meniran (Phyllanthus niruri L.) terhadap kadar trigliserida darah tikus putih (Rattus norvegicus). Thesis tidak diterbitkan, Universitas Sebelas Maret, Solo.
Kainde, R. P. S. P., Ratag, J. S., Tasirin, & Faryanti. (2011). Analisis vegetasi hutan lindung Gunung Tumpa. Jurnal Eugenia, 17(3).
Kamoltham, T., Manosroi, J., Chankhampan, C., Manosroi, W., & Manosroi, A. (2017). In vitro anti-aging activities of Centotheca lappacea (L) desv. (Ya Repair) extract. Chiang Mai J. Sci., 44(X), 1-12.
Khairiyah, N., Anam, S., & Khumaidi, A. (2016). Studi etnofarmasi tumbuhan berkhasiat obat pada suku Banggai di Kabupaten Banggai Laut, Provinsi Sulawesi Tengah. Galenika Journal of Pharmacy, 2(1), 1-7.
Kinuthia, D. G., Peter, A. W. M., & Mwangi, W. (2016). Freeze dried extracts of Bidens biternata (Lour.) Merr. and Sherry, show significant antidiarrheal activity in in-vivo models of diarrhea. Journal of Ethnopharmacology, 193, 416-422.
Kumar, S. S., John, R., & Narayanan, G. L. (2015). Antimicrobial activity of Tridax procumbens leaf. International Journal of Pharma Sciences and Research, 6(3), 517-518.
Kumar, K., Kumar, B., Selvun, T., Sajibala, B., Jairaj, R. S. C., Mehrotra, S., & Pushpangadan, P. (2006). Etnobotanical heritage of Nicobrese Trebe. J. Econ. Taxon. Bot., 30(2), 331-348.
Kuppusamy, P., Ichwan, S. J. A., Al-Zikra, P. N. H., Suriyah, W. H., Soundharrajan, H., Govindan, N., Manian, G. P., & Yussof, M. M. (2016). In vitro anticancer activity of Au, Ag nanoparticles synthesized using Commelina nudiflora L. aqueous extract againts HCT-116 colon cancer cells. Bio Trace Elem Res, 173, 297-305.
Kuppusamy, P., Havenil, S., Srigopalram, S., Kim, D. H., Govindan, N., Maniam, G. P., Yusoff, M. M., & Choi, K. C. (2017). Synthesis of bimetallic nanoparticles (Au-Ag Alloy) using Commelina nudiflora L. plant extract and study its on oral pathogenic bacteria. Journal of Inorganix and Organometallic Polymers and Materials, 27(2), 562-568.
Maisyaroh, W. (2010). Struktur komunitas tumbuhan penutup tanah di taman hutan raya. Jurnal Pembangunan dan Alam Lestari, 1(1), 1-9.
Mambang, D. E. P. (2014). Rebusan rimpang alang-alang (Imperata cylindrical L.) memberikan efek diuretik pada mencit (Mus musculus) di menit ke 90. Jurnal Ilmiah PANNMED, 8(3), 299-304.
Mazid, M. A., Datta, B. K., Nahar, L., Bashar, S. A. M. K., Bachar, S. C., & Sarker, S. D. (2009). Antinociceptive, anti-inflammatory and diuretic properties of Polyganum barbatum (L.) Hara var. Barbata. Brazilian Journal of Pharmacognosy, 19(3), 749-754.
Mazid, M. A., Nahar, L., Datta, B. K., Bashar, S. A. M. K., & Sarker, S. D. (2011). Potential antitumor activity of two Polygonum species. Arch. Bio. Sci., Belgrade, 63(2), 465-468.
Melinda, K. P., Rathinam, X., Kasi, M., Ayyalu, D., Surash, R., Sadasivam, K., & Subramaniam, S. (2010). A comparative study on the antioxidant activity of methanolic leaf extracts of Ficus religiosa L, Chromolaena odorata (L.) King & Rabinson, Cynodon dactylon (L.) Pers. And Tridax procumbens L. Asian Pacific Journal of Tropical Medicine, 348-350.
Moura, A. C. A., Silva, L. F., Fraga, C. A., Wanderlay, A. G., Afiatpur, P., & Maia, M. B. S. (2005). Antinflammatory and chronic toxicity study of the leaves of Ageratum conyzoides L. in rats. Phytomedicine, 12(1-2), 138-142.
Mukti, L. P. D., Sudarsono, & Sulistyono. (2016). Keanekaragaman jenis tumbuhan obat dan pemanfaatannya di hutan Turgo, Purwobinangun, Pakem, Sleman, Yogyakarta. Jurnal Biologi, 5(5), 9-19.
Natalia, D., & Handayani, T. (2013). Analisis vegetasi strata semak di Plawangan Taman Nasional Gunung Merapi pasca erupsi Merapi 2010. Jurnal Bioedukatika, 1(1), 62-71.
Nour, A. M. M., Khalid, S. A., Kaiser, M., Brun, R., Abdalla, W. E., & Schmidt, T. J. (2010). The antiprotozoal activity of methylated flavonoids from Ageratum conyzoides L. Journal of Ethnopharmacology, 129, 127-130.
Nworu, C. S., Akah, P. A., Okoye, F. B. C., & Esimone, C. O. (2012). Inhibition of pro-inflammatory cytokines and inducible nitric oxide by extract of Emilia sonchifolia L. aerial parts. Immunopharmacology and Immunotoxicology, Early Online, 1-7.
Odum, E. P. (1994). Fundamentals of Ecology, Third Edition. Samingan, T (Terjemahan). Yogyakarta. Gadjah Mada University Press.
Oktriandana, M. (2014). Pengaruh ekstrak daun meniran (Phyllanthus niruri, L.) terhadap pertumbuhan Stayphylococcus aureus. Thesis tidak diterbitkan, Sekolah Tinggi Agama Islam Negeri Palangka Raya, Palangka Raya.
Pakadang, S. R., Elyana, W., Pine, A. T. D., & Kurniati A. R. (2017). Potensi ekstrak daun Tempuh Wiyang (Emilia sanchifolia L. DC) sebagai anti bakteri terhadap infeksi Salmonella enetertidis pada mencit (Mus musculus). Media April 2017. Politeknik Kesehatan Makassar Jurusan Farmasi.
Parihaar, R. S., Bargali, K., & Bargali, S. S. (2014). Diversity and uses of ethno-medicinal plants associated with traditional agroforestry systems in Kumaun Himalaya. Indian Journal of Agricultural Sciences, 84(12), 1470-1476.
Petchi, R. R., Vijaya, C., & Parasuraman, S. (2013). Anti-arthritic activity of ethanolic extract of Tridax procumbens (Linn) in Sprague Dawley rats. Pharmacognosy Res, 5(2), 113-117.
Pittella, F., Dutra, R. C., Junior, D. D., Lopes, M. T. P., & Barbosa, N. R. (2009). Antioxidant and cytotoxic activities of Centella asiatica (L) Urb. Int. J. Mol. Sci, 10, 3713-3721.
Prasad, A. G. D., & Shyma, T. B. (2013). Medicinal plants used by the tribes of Vythiri taluk, Wayanad district (Kerala state) for the treatment of human and domestic animal ailments. Journal of Medicinal Plants Research, 7(20), 1439-1451.
Pratibha, P., Sophia, D., Perumal, P. C., & Gopalakrishnan, V. K. (2014). In-silico docking analysis of Emilia Sonchifolia (L.) DC gas chromatography-mass spectroscopy derived terpenoid compounds againts pancreatic cancer. World Journal of Pharmacy and Pharmaceutical Sciences, 3(6), 1844-1855.
Pyne, S. G., Liawruangrath, B., Liawruangrath, S., Garson, M., & Khamsan, S. (2011). Antimalarial, anticancer, antimicrobial activities and chemical constituents of essential oil from the aerial parts of Cyperus kyllingia Endl. Records of Natural Products, 5(4), 324-327.
Rahman, M. S., Khan, M. M. H., & Jamal, M. A. H. M. (2010). Anti-bacterial evaluation and minimum inhibitory concentration analysis of Oxalis corniculata and Ocimum santum againts bacterial pathogens. Biotechnology 2010, 1-4.
Rahman, M. A., Akter. N., Rashid, H., Ahmed, N. U., Uddin, N., & Islam, M. S. (2012). Analgesic ans anti-inflammatory effect of whole Ageratum conyzoides and Emilia Sonchifolia alcoholic extracts in animal models. African Journal of Pharmacy and Pharmacology, 6(20), 1469-1476.
Ray, S., Chatterjee, S., & Chakrabarti, C. S. (2013). Antiproliferative activity of allelochemicals presents in aqueous extract of Synedrella nodiflora (L.) Gaertn. in apical meristems and Wistar rat bone marrow cells. Iosr Journal of Pharmacy, 3(2), 1-10.
Rosadi, I. (2015). Analisis vegetasi tumbuhan Gunung Lawu jalur pendakian Cemoro Mencil Girimulyo Jogorogo Ngawi. Thesis tidak diterbitkan, Universitas Muhammadiyah Surakarta, Surakarta.
Rupa, D. (2015). Identifikasi Struktur Sekretori dan Analisis Histokimia serta Fitokimia Tumbuhan Obat Anti-Infeksi di Kawasan Taman Nasional Bukit Duabelas Jambi. Thesis tidak diterbitkan, Institut Pertanian Bogor, Bogor.
Sagar, R., & Sahoo, H. B. (2012). Evaluation of antiasthmatic activity of ethanolic extract of Elephantopus scaber L. leaves. Indian J Pharmacol, 44(3), 398-401.
Satish, S., Raghavendra, M. P., & Raveesha, K. A. (2008). Evaluation of the antibacterial potential of some plants against human pathogenc bacteria. Advances in Biological Research, 2(3-4), 44-48.
Schmidt, C., Fronza, M., Goetert, M., Geller, F., Luik, S., Flores, E. M. M., Bittencourt, C. F., Zanetti, G. D., Heinzmann, B. M., Laufer, S., & Merfort, I. (2009). Biological studies on Brazilian plants used in wound healing. Journal of Ethnopharmacology, 122, 523-532.
Sihombing, W., Akmal, M., Wahyuni, S., Nasution, I., Rinidar, & Hamdan. (2015). Efek ekstrak daun pegagan (Centella asiatica (L.) Urban) terhadap perkembangan sel spermatid tikus (Ratus norvegicus). Jurnal Medika Veterinaria, 9(1), 71-76.
Soerianegara, I., & Indrawan, A. (1988). Ekologi Hutan Indonesia. Bogor: Departemen Manajemen Hutan Fakultas Kehutanan IPB.
Sopan, N., Vijay, K., & Mendhulkar, D. (2016). Synthesis, characterization and studies on antioxidant activity of silver nanoparticles using Elephantopus scaber leaf extract. Material Science and Engineering, 62, 719-724.
Sophia, D., Ragavendran, P., Arulraj, C., & Gopalakrishnan, V. K. (2011). In vitro antioxidant activity and HPTLC determination of n-hexane extract of Emilia sonchifolia (L.) DC. Journal of Basic and Clinical Pharmacy, 002(004), 179-183.
Sreejith, G., Jayasree, M., Latha, P. G., Suja, S. R., Shyamal, S., Shine, V. J., Anuja, G. I., & Sini, S. (2014). Hepatoprotective activity of Oxalis corniculata L. ethanolic extract againts paracetamol induced hepatotoxicity in Wistar rats and its in vitro antioxidant effects. Indian Journal of Experimental Biology, 52, 147-152.
Su, M., Chung, H. Y., & Li, Y. (2011). Deoxyelephantopin from Elephantopus scaber L. induces cell-cyce arrest and apoptosis in the human nasopharyngeal cancer CNE celss. Biochemical and Biophysical Research Communications, 411(2), 342-347.
Sudipta, B., Kumar, D. S., Goutam, P., & Monalisha, D. (2012). Evaluation of antidiabetic activity and histological study of Cyperus kyllinga Endl. roots. Indian Journal of Natural Products and Resources, 3(3), 343-346.
Sugara, T. H., Irawadi, T. T., Suprapto, I. H., & Hanafi, M. (2016). Uji aktivitas anti bakteri fraksi etil asetat daun tanaman bandotan (Ageratum conyzoides L.). Jurnal Ilmiah Ibnu Sina, 1(1), 88-96.
Suharti, S. (2015). Pemanfaatan tumbuhan bawah di zona pemanfaatan Taman Nasional Gunung Merapi oleh masyarakat sekitar hutan. dalam Setyawan, A. D., Sugiyarto, Pitoyo, A., Hernawan, U. E., Sutomo, Widiastuti, A., Raqib, S. M., Suwandhi, I., Rosleine, D., Syamsudin, T., Iskandar, J., Simbala, H. E. I., Kilowasid, L. M. H. (eds) Seminar Nasional Masyarakat Biodiversitas Indonesia (p.1411-1415). Surakarta: Masyarakat Biodiversitas Indonesia, Program Biosains Program Pasca Sarjana Universitas Sebelas Maret Surakarta, Jurusan Biologi MIPA Universitas Sebelas Maret Surakarta.
Sujono, T. A., Hidayah, U. N. W., & Sulaiman, T. N. S. (2014). Efek gel ekstrak herba pegagan (Centella asiatica L. Urban) dengan gelling agent hidroksipropil methylcellulose terhadap penyembuhan luka bakar pada kulit punggung kelinci. Biomedika, 6(2), 9-17.
Sukumaran, P., Nair, A. G., Chinmayee, D. M., Mini, I., & Sukumaran, S. T. (2012). Phytochemical investigation of Bidens biternata (Lour.) Merr. And Sheriff, _ a nutrient-rich leafy vegetable from Western Ghats of India. Applied Biochemistry and Biotechnology, 167(6), 1795-1801.
Sutardi. (2016) Kandungan bahan aktif tanaman pegagan dan khasiatnya untuk meningkatkan sistem imun tubuh, Jurnal Litbang Pertanian, 35(3), 121-130.
Tona, L., Mesia, K., Ngimbi, N. P., Chrimwami, B., Okond’ahoka, & Cimanga, K. (2001). In-vivo antimalarial activity of Cassia occidentalism, Morinda morindoides, and Phyllanthus niruri. Annals of Tropical Medicine & Parasitology, 95(1), 45-57.
Wahyuningsih, H. K. (2010). Pengaruh pemberian ekstrak herba meniran (Phyllanthus niruri L.) terhadap penurunan kadar asam urat darah tikus putih jantan hiperurisemia. Thesis tidak diterbitkan, Universitas Sebelas Maret, Surakarta.
Yatim, W. (1999). Kamus Biologi Edisi Pertama. Jakarta:Yayasan Obor Indonesia
Yoga L. L. Jr., Darah, I., Saidharan, S., & Jain, K. (2009). Antimicrobial activity of Emilia sonchifolia DC., Tridax procumbens L. and Vernonia cinerea L. of Asteracea family: potential as food preservations. Malaysian Journal of Nutrition, 15(2), 223-231.
Yuskianti, V., Rahayu, S. K. D., & Handayani, T. (2018). Keanekaragaman paku terestrial di Kawasan Hutan Dengan Tujuan Khusus (KHDTK) Kaliurang Yogyakarta. Bioedukasi, 11(2), 85-92.
Zhang, F. -P., Zheng, M. -Q., & Wu, M. -J. (2012). Extraction and antioxidant activity of flavonoids from Gynura crepidioides. Food Science, 22.
DOI: https://doi.org/10.20886/jwas.v6i1.5057